The aim of this study is to manipulate musical cues systematically to determine the aspects of music that contribute to emotional expression, and whether these cues operate in additive or interactive fashion, and whether the cue levels can be characterized as linear or non-linear. An optimized factorial design was used with six primary musical cues (mode, tempo, dynamics, articulation, timbre, ...

the solubility enhancement of poorly soluble compounds is an important task in pharmaceutical technology as it leads to better bioavailability and a more efficient application. fused dispersions (fds) of simvastatin (sim) using peo-ppo block copolymer were prepared which paved the way for the formation of an amorphous product with enhanced dissolution and bioavailability. the accumulative solub...

The objective of the current study was to develop and optimize a novel lyophilized liposomal formulation anticancer agent carmustine, or bis-chloroethyl nitrosourea (BCNU) for prolonged release that could overcome dose-dependent side effects improve its bioavailability at site action. optimization done using 32 factorial design approach wherein soya phosphatidylcholine (SPC) cholesterol (CH) as...